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نوع الوثيقة |
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مقال في مجلة دورية |
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عنوان الوثيقة |
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Novel methods for the synthesis of some pyridazino-, furo-, and polysubstituted pyridazines Novel methods for the synthesis of some pyridazino-, furo-, and polysubstituted pyridazines |
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لغة الوثيقة |
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العربية |
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المستخلص |
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3,4-Diethoxycarbonyl-5,6-diphenylpyridazine 1 reacted with hydrazine hydrate to form tetrahydropyridazino [4,5-c]pyridazine 2, which reacted with ethyl bromoacetate to give 6,7-diethoxycarbonylmethyl-3,4-diphenyl-5,8-dioxopyridazino[4,5-c]pyridazine 3. However, acetylation of 2 with acetyl chloride gave three different pyridazino[4,5-c]pyridazines 4-6. The reaction of the starting diester 1 with different amounts of phenylmagnesium bromide gave different products 7-10. The structure of product 8 was elucidated by alkaline hydrolysis and hydrazinolysis to afford 11 and 13, respectively. Treatment of 13 with benzaldehyde in piperidine yielded the starting Grignard product 8 and benzalazine 17. |
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اسم الدورية |
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SYNTHETIC COMMUNICATIONS |
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المجلد |
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32 |
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العدد |
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7 |
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سنة النشر |
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2002 هـ
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تاريخ الاضافة على الموقع |
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Monday, June 23, 2008 |
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الباحثون
| سوزان محمد بترجي | Batterjee S | باحث | | |
| . | Shams NA | باحث | | |
| . | El-Shahawi MM | باحث | | |
| . | Shalaby AA | باحث | | |
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